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Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

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Abstract Background Alternative splicing of the Pkm gene product generates the PKM1 and PKM2 isoforms of the glycolytic enzyme pyruvate kinase. PKM2 expression is associated with embryogenesis. tissue regeneration. and cancer. https://www.roneverhart.com/Cleglaw-s-Tooth-West-Ladder/
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